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Apply a pea-sized amount or less to a clean and dry face. Limit initial use to once or twice a week, gradually increasing frequency to every other night and then finally up to every night (as tolerated).Proceed with caution if you're sensitive or new to retinol - this may induce redness/irritation to begin with and you may incur some flakiness until your skin acclimatises. Avoid using the night before a big event/special occasion (unless you're already a retinol addict)!
Avoid applying to eye area and use a broad spectrum SPF during the day.